Table 1. Demographic and clinical characteristics of the study subjects with and without RLS.
| Characteristic | All subjects | RLS during pregnancy | p | |
|---|---|---|---|---|
| (n=214) | No (n=190) | Yes (n=24) | ||
| Age, years | 28.60±6.52 | 28.73±6.53 | 27.58±6.54 | 0.42 |
| BMI, before pregnancy | 22.55±4.46 | 22.58±4.55 | 22.31±3.69 | 0.75 |
| BMI, third trimester | 27.69±4.67 | 27.73±4.80 | 27.43±3.58 | 0.71 |
| Hb, g/dL | 11.76±1.22 | 11.83±1.22 | 11.21±1.11 | 0.02 |
| Hematocrit, % | 35.98±3.53 | 36.12±3.60 | 34.94±2.79 | 0.13 |
| MCV, fL | 81.72±8.68 | 81.78±8.90 | 81.21±6.83 | 0.76 |
| Multigravida | 83 (38.8) | 74 (38.9) | 9 (37.5) | 0.89 |
| Multiparity | 45 (21.0) | 40 (21.1) | 5 (20.8) | 0.98 |
| History of abortion | 34 (15.9) | 29 (15.3) | 5 (20.8) | 0.48 |
| Diabetes mellitus | 10 (4.7) | 9 (4.7) | 1 (4.2) | 0.90 |
| Thyroid disease | 1 (0.5) | 0 | 1 (4.2) | <0.01 |
| Hypertension | 10 (4.7) | 8 (4.2) | 2 (8.3) | 0.37 |
| Anemia (Hb <11 g/dL) | 45 (21.0) | 34 (17.9) | 11 (45.8) | <0.01 |
| Past smoking | 13 (6.1) | 11 (5.8) | 2 (8.3) | 0.62 |
| Past alcohol | 27 (12.6) | 23 (12.1) | 4 (16.7) | 0.53 |
| Past caffeine | 43 (20.1) | 37 (19.5) | 6 (25) | 0.52 |
| History of RLS | 4 (1.9) | 1 (0.5) | 3 (12.5) | <0.01 |
| Family history of RLS | 1 (0.5) | 0 | 1 (4.2) | <0.01 |
| Delivery complications | 35 (16.4) | 21 (11.1) | 3 (12.5) | 0.58 |
| Female newborn | 123 (57.5) | 112 (58.9) | 11 (45.8) | 0.22 |
| Preterm labor | 36 (16.8) | 31 (16.3) | 5 (20.8) | 0.58 |
| Cesarean section | 68 (31.8) | 61 (32.1) | 7 (29.2) | 0.77 |
| Apgar score | 8.84±0.73 | 8.86±0.73 | 8.71±0.75 | 0.35 |
| Birthweight, g | 3001.1±463.1 | 3013.8±461.7 | 2899.8±471.8 | 0.26 |
Data are mean±SD or n (%) values.
BMI: body mass index, Hb: hemoglobin level, MCV: mean corpuscular volume, RLS: restless legs syndrome.