Table 1. Comparison of baseline characteristics between patients with and without AD.
| Characteristic | No AD (n=2,269) | AD (n=357) | p |
|---|---|---|---|
| Demographics | |||
| Age, years | 65.4±7.8 | 71.7±8.2 | <0.01 |
| Sex, female | 1,161 (51.2) | 194 (54.3) | <0.05 |
| Low education level, ≤6 years | 547 (24.1) | 101 (28.3) | <0.01 |
| BMI, kg/m2 | 23.5±3.1 | 24.1±3.2 | 0.27 |
| Vascular risk factors | |||
| Hypertension | 615 (27.1) | 115 (32.2) | <0.01 |
| Hyperlipidemia | 517 (22.8) | 96 (26.9) | <0.01 |
| Diabetes | 533 (23.5) | 94 (26.3) | <0.05 |
| Current smoking | 361 (15.9) | 67 (18.8) | <0.05 |
| Daily alcohol consumption | 309 (13.6) | 59 (16.5) | <0.05 |
| Coronary artery disease | 329 (14.5) | 59 (16.5) | <0.08 |
| History of stroke | 481 (21.2) | 80 (22.4) | <0.18 |
| Blood indexes | |||
| ApoE, mg/L | 33.21±16.81 | 35.41±14.23 | <0.05 |
| Hcy, mmol/L | 18.22±6.79 | 18.97±8.01 | <0.12 |
| hs-CRP, mg/L | 5.61±1.24 | 5.55±1.19 | <0.38 |
| Cognition assessment | |||
| MMSE score | 29.6±2.62 | 28.8±2.32 | <0.15 |
| ADL score | 12.8±2.14 | 13.4±2.43 | <0.13 |
Data are mean±SD or n (%) values.
AD: Alzheimer's disease, ADL: Activities of Daily Living, BMI: body mass index, Hcy: homocysteine, hs-CRP: high-sensitivity C-reactive protein, MMSE: Mini Mental State Examination.