Table 2. Comparison of severities of WMH and LI between patients with and without AD.
| Characteristic | No AD (n=2,26 9) | AD (n=357) | p |
|---|---|---|---|
| WMH | <0.01 | ||
| None | 1,560 (68.7) | 210 (58.8) | |
| Mild | 366 (16.1) | 59 (16.5) | |
| Moderate | 217 (9.6) | 50 (14.1) | |
| Severe | 126 (5.6) | 38 (10.6) | |
| LI | <0.05 | ||
| None | 1,853 (81.8) | 277 (77.6) | |
| A few (1 to 3) | 279 (12.2) | 45 (12.6) | |
| Many (≥4) | 137 (6.0) | 35 (9.8) | |
| WMH and LI | <0.01 | ||
| Neither WMH nor LI | 818 (36.1) | 49 (13.7) | |
| Only WMH | 709 (31.2) | 147 (41.2) | |
| Only LI | 416 (18.3) | 80 (22.4) | |
| Both WMH and LI | 326 (14.4) | 81 (22.7) |
Data are n (%) values.
AD: Alzheimer's disease, LI: lacunar infarcts, WMH: white-matter hyperintensities.