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. 2018 Dec 1;8(12):2507–2517.

Figure 6.

Figure 6

MiR-485-5p overexpression suppresses glioma growth in vivo. (A) Tumor growth curves after subcutaneous injection of nude mice with U87 cells. MiR-NC or miR-485-5p was injected intratumorally into each subcutaneous tumor every 3 d. Tumor volumes were measured every 3 d from days 7 to 28. (B-F) Analysis of miR-NC group and miR-485-5p group tumors on day 28 after injection: tumor images (B); tumor weights (C); miR-485-5p expression (D); PAX3 and p-JNK expression (E); immunohistochemical staining of Ki-67 (F). Data were expressed as the mean ± SEM from three independent experiments. *P < 0.05.