Skip to main content
. 2018 Dec 1;8(12):2402–2418.

Figure 2.

Figure 2

Cell proliferation in the PC cell lines following treatment CUDC-101 with/or gemcitabine. A. Cell viability of PANC-1 and MIA PaCa-2 treated with the CUDC-101 or gemcitabine for 48 h was measured by MTT assay. B. The combination index was calculated according to the approach described by Chou and Talalay. CI = 1 indicates an additive effect, CI < 1 a synergistic effect, and CI > 1 an antagonistic effect. C. Combination of CUDC-101 and gemcitabine synergistically inhibited the viability of PC cells compared with single agents (*P < 0.05, ***P < 0.0001). D. CUDC-101 and gemcitabine synergistically inhibited the colony formation of PANC-1 and MIA PaCa-2 cells by the plate colony forming assay. E. CFSE staining in control and treated mammospheres.