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. 2018 Dec 1;8(12):2387–2401.

Figure 3.

Figure 3

Silence of miR-203a-3p by sponges significantly reduced CRC cell proliferation and colony formation, promoted apoptosis. (A, B) HCT116 and SW1116 cells were infected with miR-203a-3p-sp or negative control lenti-virus and Quantitative RT-PCR used to determine miR-203a-3p expression. (C, D) miR-203a-3p-sp significantly reduced cell proliferation (C) and clone formation (D) in HCT116 and SW1116 cells. (E) miR-203a-3p-sp significantly promoted cell apoptosis in HCT116 and SW1116 cells. Each assay was repeated three times. The data represent means ± SD of three independent experiments. *P < 0.05; **P < 0.01; ***P < 0.001.