Table 2.
Univariate Cox regression analysis for the prognostic value of GALNT6 expression and clinicopathological features in CRC
| Characteristics | GALNT6 expression | Hazard ratio | 95% CI | P value | ||
|---|---|---|---|---|---|---|
|
| ||||||
| Low (%) | High (%) | |||||
| Gender | Male | 13 (27.7) | 34 (72.3) | 0.623 | ||
| Female | 13 (35.1) | 24 (64.9) | ||||
| Age (years) | ≥ 60 | 17 (34.7) | 32 (65.3) | 0.822 | ||
| < 60 | 9 (25.7) | 26 (74.3) | ||||
| Tumor size (cm) | ≥ 5 | 15 (37.5) | 25 (62.5) | 1.317 | 1.115~1.555 | 0.001 |
| < 5 | 11 (25.0) | 33 (75.0) | ||||
| Histological differentiation | Well | 3 (16.7) | 15 (83.3) | 0.384 | 0.201~0.735 | 0.004 |
| Moderately | 8 (21.1) | 30 (78.9) | ||||
| Poorly | 15 (53.6) | 13 (46.4) | ||||
| Dukes Staging | A | 0 (0.0) | 5 (100.0) | 3.722 | 2.114~6.553 | 0.000 |
| B | 8 (20.5) | 31 (79.5) | ||||
| C | 14 (46.7) | 16 (53.3) | ||||
| D | 4 (40.0) | 6 (60.0) | ||||
| T classification | T1 | 0 (0.0) | 2 (100.0) | 0.227 | ||
| T2 | 3 (23.1) | 10 (76.9) | ||||
| T3+T4 | 23 (33.3) | 46 (66.7) | ||||
| N classification | No | 16 (45.7) | 19 (54.3) | 2.372 | 1.026 ~5.484 | 0.043 |
| N1+N2 | 10 (20.4) | 39 (79.6) | ||||
| M classification | M0 | 4 (33.3) | 8 (66.7) | 6.971 | 2.941~16.519 | 0.000 |
| M1 | 22 (30.6) | 50 (69.4) | ||||
| GALNT6 expression | Low | 0.846 | 0.733~0.977 | 0.023 | ||
| High | ||||||