Figure 3.

Results of chemotherapeutic drug sensitivity assays in 786-O SFCs and MACs. Approximately 2,000 SFCs and MACs were plated in 96-well flat-bottom plates. Different chemotherapeutic agents along a concentration gradient were added to the plates on the following day and in three replicate wells. Cell viability was evaluated after 2 days of drug treatment by the MTT (Sigma) assay. 786-O SFCs were more resistant to anticancer drugs doxorubicin (A), mitomycin C (B) and cisplatin (C) than were MACs. **P < 0.01. The experiment has been repeated twice.