Table 2.
Association of WNT10A methylation with clinical characteristics of CRC in TCGA cohorts
Characteristics | N | Mean methylation | P | |
---|---|---|---|---|
Gender | Male | 212 | 33% | 0.11 |
Female | 182 | 35% | ||
Age (year) | ≤ 60 | 153 | 32% | 0.037* |
> 60 | 241 | 35% | ||
Stage | I | 58 | 31% | 0.12 |
II | 153 | 34% | ||
III | 127 | 34% | ||
IV | 56 | 35% | ||
Lymph metastasis | No | 217 | 33% | 0.31 |
Yes | 177 | 34% | ||
Distant metastasis | No | 341 | 31% | 0.033* |
Yes | 53 | 34% | ||
Tumor location | Colon | 296 | 32% | 0.03* |
Rectum | 98 | 35% | ||
Histological classification | Adenocarcinoma | 344 | 33% | 0.02* |
Mucinous adenocarcinoma | 50 | 37% |
P < 0.05.