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. 2018 Dec 15;10(12):4141–4151.

Figure 5.

Figure 5

ISL reduced phosphorylation of NF-κB p65 upon LPS administration. A-D. Effects of ISL on pp65 in total were measured by western blot. LPS increased the expression of pp65 in total. ISL treatment can decrease pp65 both in mice and cells. E-H. Effects of ISL on pp65 in nuclear were measured by western blot. There is no significant difference between ISL group and Ctrl group. But ISL can decrease pp65 in nuclear on LPS-induced mouse model. *P < 0.05 vs. the LPS group, ***P < 0.001 vs. the LPS group, #P < 0.001 vs. the Ctrl group, ###P < 0.001 vs. the Ctrl group.