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The viability of PDAC cells in which ARK5 was knocked down cultured in different concentrations of gemcitabine (Gem)
| Cell lines | IC50 (μM) | |
|---|---|---|
|
| ||
| Negative siRNA+Gem | ARK5 siRNA+Gem | |
| CFPAC-1 | 0.2135 (0.1953 to 0.2349) | 1.269 (0.9429 to 1.594) |
| BxPC-3 | 2.40 (2.113 to 2.687) | 1.269 (0.9429 to 1.594) |
| MIA PaCa-2 | 11.84 (11.13 to 12.56) | 6.852 (6.235 to 7.469) |
| PAN-198 | 45.63 (42.43 to 48.83) | 28.33 (26.95 to 29.70) |
IC50 values show gemcitabine concentration [μM. mean (95% confidence intervals)].
