Figure 3.

Effect of RDN on plasma renin activity (A) and aldosterone (B) at the age of 48 weeks. Asterisk indicates statistical significance (P < 0.01) vs sham operated rats; NS, not significant; the statistical significance is indicated by the sharp (P < 0.01 vs WKY-Sham) and dagger (P < 0.01 vs WKY-RDN). Values are mean ± standard deviation; N = 10 in each group; WKY-Sham indicates sham-operated Wistar-Kyoto rats; WKY-RDN, Wistar-Kyoto rats subjected to renal denervation; SHR-Sham, sham-operated spontaneously hypertensive rats, SHR-RDN, spontaneously hypertensive rats subjected to renal denervation.