Figure 3.

Inhibition of BLA→NAc pathway after risky losses increases risky choice. A, Optogenetic manipulation and task design. Laser light was delivered for 7 s on trials when the large/risky lever was chosen and no reward was delivered. B, Inhibition during risky losses increased choice of the large/risky option during the low probability block (n = 15). Inset, Win-stay/lose-shift data. The increase in risky choice was not associated with changes in win-stay/lose-shift behavior. C, Individual data. In the majority of rats tested, optogenetic inhibition after risky losses increased risky choice relative to baseline in the 12.5% probability blocks.