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. 2018 Dec 21;5(6):ENEURO.0328-18.2018. doi: 10.1523/ENEURO.0328-18.2018

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Copyright © 2018 Gaudet et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 5. — SCI in female and male rats disrupted diurnal rhythms in activity. Data show cumulative activity counts per 3 h time period. Before surgery, female and male rats exhibited typical diurnal rhythms in activity, with rats more active in the dark phase. As expected, SCI rats were less active at acute times postinjury (up to 7 d postsurgery). Interestingly, at subacute (14 d postsurgery) to chronic times, SCI rats regained activity levels and diurnal rhythms in activity that were similar to those of sham rats. *p < 0.05 for sham vs SCI at that time point, ANOVA with Holm–Sidak post hoc test.