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. 2018 Nov 8;6(1):1801260. doi: 10.1002/advs.201801260

Figure 10.

Figure 10

Bio‐distribution and metabolism of Si and acute toxicity of “ion therapy.” a) Serum Si concentrations after initiation injection in AMI mouse (n = 4). b) Serum Ca ion concentrations after initiation injection in AMI mouse (n = 4). c) Si concentrations in hearts before and after “ion therapy” for 1, 7, 14, 21, and 28 d (n = 3 for each group). d) Si concentrations in lungs before and after “ion therapy” for 1, 7, 14, 21, and 28 d (n = 3 for each group). e) Si concentrations in kidneys before and after “ion therapy” for 1, 7, 14, 21, and 28 d (n = 3 for each group). f) Si concentrations in liver before and after “ion therapy” for 1, 7, 14, 21, and 28 d (n = 3 for each group). g) Serum expression of ALT, AST, and Cr level in each groups after injection for 7 d. h) Serum expression of ALT, AST, and Cr level in each groups after injection for 14 d. Sham group n = 4; AMI group n = 7 and AMI+CS group n = 13. *p < 0.05 versus sham group or day 0, **p < 0.01 versus Day 0, †p < 0.05 versus AMI group; mean ± SD.