Skip to main content
. 2018 Dec 13;7:359. Originally published 2018 Mar 22. [Version 2] doi: 10.12688/f1000research.14227.2

Figure 5. MED12 mutations in uterine smooth muscle tissue.

Figure 5.

Model illustrating the occurrence and selection of MED12 mutations during the course of leiomyoma development. The scheme suggests that of a larger number of MED12-mutations only those associated with a gain of function act as driver mutations giving rise to UL.