Figure 8. Model depicting the interaction between bacterial RNA with the MED12 mutational hotspot and similarity of the corresponding palindromic structure in different species of Staphylococcus.

As an example for the putative sequence of the human microbiome inducing site specific mutations this scheme refers to the sequence depicted in Figure 7 ( A). A similar palindromic structure is present at the same position of some other Staphylococcus species as shown here as examples for S. argenteus and S. pseudointermedius, respectively (green squares). ( B)