Table 3.

Potential impacts of the pre-exposure prophylaxis (PrEP) Optimization Intervention on the provision of PrEP.

Intervention component and impact on PrEPa prescribing		Example quotes
PrEP-Rx
	Knowledge base providing quick references and information related to PrEP	...it streamlines all the important elements that you’d want to know for a discussion with the patient. It lays out things clearly so it’s easy to see all the things in follow-up. Timeline gives a summary and walks you through the steps and is laid out in a structured way. [HCP #3]
	Ability to provide all necessary data for all patients on PrEP in 1 comprehensive streamlined format, resulting in increased ease of PrEP prescription and being more effective	...being able to look at the information on risk and timeline and having patients teed up, is very helpful and so much easier than current HER...it makes me so much more effective as a provider of PrEP. [HCP #4]
	Allowing for the PrEP coordinator to function more effectively	The survey goes into so much detail that would take a really long time as a provider to go into and it would be unlikely to get into this exact level of detail without a fairly involved visit especially for someone you’re meeting for the first time...We’re always focused on time as providers, so overcoming that hurdle of how many different screens do I need to click through to figure out...all their labs, trying to have all their follow-up, and really just the survey being so detailed. That would overcome a lot of the energy to do this in a reasonable amount of time for the provider and the patient. [HCP #6]
PrEP coordinator
	Increasing patient engagement in health care and retention	[the PrEP coordinator] is the “glue” as far as getting the person in and encouraging them to come in...it is undoable without [the PrEP coordinator]. [HCP #4]
	Improving communication between health care providers and patients	...having multiple touch points for the patient can be really helpful...the more likely you are to get someone engaged and sustained... [HCP #6]
PrEP Rx + PrEP coordinator
	Helping keep patients healthy by improving monitoring and follow-up	...it motivates in as much as it’s linked to the patient. Because for providers that’s where our motivation is: to keep our patients healthy and happy...I think that thinking about how this is helping my patients and how this is helping reduce their HIV risk, is a motivation for me... [HCP #3]
	Reducing loss to follow-up	It makes me capable and motivates me because I know my patients are getting good care and know when my patients have fallen out of care. [HCP #4]

^aPrEP: pre-exposure prophylaxis.