Figure 3.

Diversity and temporal distribution of meningococcal serogroup C case isolates, England, 2010/11–2015/16

A) Neighbor-net phylogenetic network based on a comparison of 1,546 core genes among all available cc11 genomes on the PubMLST database, excluding predominantly-serogroup W lineage 11.1 sublineages (final n = 898; accessed 07/10/16). The English meningococcal serogroup C case isolates from 2010/11 to 2015/16 (red dots) were mainly distributed among several closely related lineage 11.1 and lineage 11.2 clusters, respectively. B) Cases due to lineage 11.1 isolates have increased since 2010/11, whilst C) cases due to lineage 11.2 isolates have fluctuated.