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. 2019 Jan 8;19:38. doi: 10.1186/s12885-018-5242-4

Table 2.

Differences between HER2 evaluation in tumors of the upper gastrointestinal tract and breast cancer

Tumors of the upper gastrointestinal tract Breast cancer
Threshold ≥ 5 positive tumor cells of biopsies; ≥ 10% surgical specimen ≥ 10% positive tumor cells
Expression pattern (baso)-lateral circular