Fig. 4.

Expression profile of DmFKBP12 protein at early gastrulation stage of the Drosophila embryo. a–d and i H&E staining of embryo at early gastrulation stage. Three germ layers are developed and the mouth of the posterior invagination was forced anteriorly. e–h and j–l display the distribution of DmFKBP12 protein at early gastrulation stage. DmFKBP12 was mainly expressed in the developing gut, muscle and neuroblasts. i–l present earlier gastrulae in e–h. The qualifications of DmFKBP12 distribution in early gastrulae are presented in m. Scale bar for a, e and i–j is 80 µm, for b–d, f–h and k–l is 40 µm. AP, anterior pole of egg; PP, posterior pole of egg; NBL, neuroblasts; ST, stomodaeum; YK, yolk; HG, hindgut; PMG, posterior midgut rudiment; GB, germ band; BR, brain, supraesophageal ganglion; MG, midgut; VNS, ventral nervous system. Data are expressed as mean ± SEM. *p < 0.05, **p < 0.01 and ***p < 0.001