Table 2.
Gene | SNP ID | Chr: Position | Role | Alleles | Nucleotide change | MAF | O(HET) | E(HET) | p-value for HWE | Call rate (%) | |
---|---|---|---|---|---|---|---|---|---|---|---|
(minor/major) | Cases | Controls | |||||||||
NR5A2 | rs2246209 | 1:200145533 | UTR-3 | A/G | 2195G > A | 0.301 | 0.313 | 0.417 | 0.430 | 0.553 | 100% |
NR5A2 | rs1056426 | 1:200146403 | UTR-3 | C/T | 3065 T > C | 0.225 | 0.238 | 0.367 | 0.363 | 0.889 | 99.72% |
LPP | rs1064607 | 3:188595672 | UTR-3 | C/G | 3405G > C | 0.405 | 0.365 | 0.453 | 0.463 | 0.661 | 99.86% |
LPP | rs3796283 | 3:188602952 | UTR-3 | G/A | 10684A > G | 0.447 | 0.414 | 0.474 | 0.485 | 0.674 | 99.86% |
LPP | rs2378456 | 3:188603007 | UTR-3 | C/G | 10739C > G, | 0.473 | 0.453 | 0.483 | 0.496 | 0.608 | 99.01% |
TNS3 | rs3750163 | 7:47317510 | UTR-3 | A/G | 164G > A | 0.087 | 0.079 | 0.148 | 0.146 | 1.000 | 100% |
TNS3 | rs9876 | 7:47315291 | UTR-3 | A/G | 2383G > A | 0.475 | 0.487 | 0.464 | 0.500 | 0.154 | 99.86% |
SNP single nucleotide polymorphism, MAF minor allele frequency, O(HET) observed heterozygosity, E(HET) expected heterozygosity, HWE Hardy-Weinberg equilibrium. p values were calculated with Pearson′s χ2 tests; p < 0.05 indicates statistical significance