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. 2019 Jan 8;19:35. doi: 10.1186/s12885-018-5241-5

Table 2.

Basic Information about the candidate SNPs in this study

Gene SNP ID Chr: Position Role Alleles Nucleotide change MAF O(HET) E(HET) p-value for HWE Call rate (%)
(minor/major) Cases Controls
NR5A2 rs2246209 1:200145533 UTR-3 A/G 2195G > A 0.301 0.313 0.417 0.430 0.553 100%
NR5A2 rs1056426 1:200146403 UTR-3 C/T 3065 T > C 0.225 0.238 0.367 0.363 0.889 99.72%
LPP rs1064607 3:188595672 UTR-3 C/G 3405G > C 0.405 0.365 0.453 0.463 0.661 99.86%
LPP rs3796283 3:188602952 UTR-3 G/A 10684A > G 0.447 0.414 0.474 0.485 0.674 99.86%
LPP rs2378456 3:188603007 UTR-3 C/G 10739C > G, 0.473 0.453 0.483 0.496 0.608 99.01%
TNS3 rs3750163 7:47317510 UTR-3 A/G 164G > A 0.087 0.079 0.148 0.146 1.000 100%
TNS3 rs9876 7:47315291 UTR-3 A/G 2383G > A 0.475 0.487 0.464 0.500 0.154 99.86%

SNP single nucleotide polymorphism, MAF minor allele frequency, O(HET) observed heterozygosity, E(HET) expected heterozygosity, HWE Hardy-Weinberg equilibrium. p values were calculated with Pearson′s χ2 tests; p < 0.05 indicates statistical significance