Table 2.
Changes of drug sensitivity in 88 treatment-failure HIV/AIDS cases
| Drugs/Frequency | Grade of DR(N/%) | ||||
|---|---|---|---|---|---|
| Susceptible | Potential resistance | Low-level resistance | Intermediate resistance | High-level resistance | |
| 3TC | |||||
| T1 | 72 (81.82) | – | – | – | 16 (18.18) |
| T2 | 70 (79.55) | – | – | – | 18 (20.45) |
| T3 | 69 (78.41) | 1 (1.14) | – | – | 18 (20.45) |
| AZT | |||||
| T1 | 83 (94.32) | 1 (1.14) | 1 (1.14) | – | 3 (3.41) |
| T2 | 77 (87.50) | 3 (3.41) | 1 (1.14) | 4 (4.55) | 3 (3.41) |
| T3 | 75 (85.23) | 4 (4.55) | 2 (2.27) | 2 (2.27) | 5 (5.68) |
| D4T | |||||
| T1 | 82 (93.18) | 2 (2.27) | – | 1 (1.14) | 3 (3.41) |
| T2 | 75 (85.23) | 3 (3.41) | 3 (3.41) | 4 (4.55) | 3 (3.41) |
| T3 | 72 (81.82) | 4 (4.55) | 3 (3.41) | 3 (3.41) | 6 (6.82) |
| TDF | |||||
| T1 | 81 (92.05) | – | 3 (3.41) | 1 (1.14) | 3 (3.41) |
| T2 | 82 (93.18) | – | 2 (2.27) | 1 (1.14) | 3 (3.41) |
| T3 | 78 (88.64) | – | 5 (5.68) | 2 (2.27) | 3 (3.41) |
| EFV | |||||
| T1 | 51 (57.95) | 6 (6.82) | 3 (3.41) | 8 (9.09) | 20 (22.73) |
| T2 | 50 (56.82) | 6 (6.82) | 2 (2.27) | 9 (10.23) | 21 (23.86) |
| T3 | 52 (59.09) | 6 (6.82) | 1 (1.14) | 7 (7.95) | 22 (25.00) |
| ETR | |||||
| T1 | 61 (69.32) | 13 (14.77) | 6 (6.82) | 7 (7.95) | 1 (1.14) |
| T2 | 58 (65.91) | 11 (12.50) | 5 (5.68) | 10 (11.36) | 4 (4.55) |
| T3 | 57 (64.77) | 13 (14.77) | 4 (4.55) | 9 (10.23) | 5 (5.68) |
| NVP | |||||
| T1 | 53 (60.23) | 5 (5.68) | 1 (1.14) | 2 (2.27) | 27 (30.68) |
| T2 | 51 (57.95) | 5 (5.68) | 1 (1.14) | 2 (2.27) | 29 (32.95) |
| T3 | 51 (57.95) | 6 (6.82) | 1 (1.14) | 1 (1.14) | 29 (32.95) |
| LPV/r | |||||
| T1 | 87 (98.86) | – | – | – | 1 (1.14) |
| T2 | 85 (96.59) | – | – | 1 (1.14) | 2 (2.27) |
| T3 | 84 (95.45) | – | – | 1 (1.14) | 2 (2.27) |
T1: First detection, T2, T3 and the like