Table 2.
Association between RET expression and clinicopathological parameters
| Clinicopathologic parameter | RET-positive | RET-negative | p value | ||
|---|---|---|---|---|---|
| Mean tumour size (mm) ± SD | 31 ± 17 | 32 ± 18 | 0.309 | ||
| Mean age at diagnosis (years) ± SD | 64 ± 14 | 64 ± 14 | 0.550 | ||
| (n) | (%) | (n) | (%) | ||
| Tumour stage | 0.546 | ||||
| pT1 | 99 | 41.9 | 137 | 58.1 | |
| pT2 | 224 | 41.4 | 317 | 58.6 | |
| pT3 | 39 | 45.9 | 46 | 54.1 | |
| pT4 | 46 | 36.2 | 81 | 63.8 | |
| NA | 1 | 100 | 0 | 0 | |
| Lymph node involvement | 0.468 | ||||
| pN0 | 201 | 39.6 | 307 | 60.4 | |
| pN1 | 163 | 44.1 | 207 | 55.9 | |
| pN2 | 37 | 37.8 | 61 | 62.2 | |
| pN3 | 4 | 50.0 | 4 | 50.0 | |
| NA | 4 | 66.7 | 2 | 33.3 | |
| Tumour grade | 0.401 | ||||
| 1 | 91 | 44.2 | 115 | 55.8 | |
| 2 | 137 | 38.7 | 217 | 61.3 | |
| 3 | 181 | 42.2 | 248 | 57.8 | |
| NA | 0 | 0 | 1 | 100 | |
| Oestrogen receptor | < 0.0001 | ||||
| ER+ | 295 | 46.0 | 347 | 54.0 | |
| ER− | 114 | 32.8 | 234 | 67.2 | |
| HER2 | 0.666 | ||||
| HER2+ | 72 | 43.1 | 95 | 56.9 | |
| HER2− | 337 | 40.9 | 486 | 59.1 | |
| Ki67 | 0.635 | ||||
| Ki67-high | 331 | 41.7 | 463 | 58.3 | |
| Ki67-low | 75 | 39.5 | 115 | 60.5 | |
| NA | 3 | 50.0 | 3 | 50.0 | |