Table 1.
Baseline patient characteristics*
| Variables | All (n=5114) | In-center (n=4234) | Home (n=880) | p-value |
|---|---|---|---|---|
| Mean age, years | 60.3 ±14 | 60.9 ±14 | 57.3 ± 15 | <0.01 |
| Male | 2864 (56) | 2371 (56) | 475 (54) | 0.25 |
| Hispanic ethnicity | 563 (11) | 466 (11) | 70 (8) | <0.01 |
| Black race | 1176 (23) | 931 (22) | 220 (25) | 0.07 |
| Mean annual household income, dollars/year | 50888 ± 19073 | 50901 ±19098 | 50828 ± 18960 | 0.92 |
| Education (bachelors and higher) | 2762 (54) | 2286 (54) | 493 (56) | <0.01 |
| Married | 2148 (42) | 1778 (42) | 396 (45) | 0.10 |
| Mean number of comorbidities | 16 ± 9 | 17 ± 9 | 15 ± 10 | <0.01 |
| Cancer | 276 (5) | 243 (6) | 33 (4) | 0.01 |
| Diabetes | 3158 (62) | 2711 (64) | 447 (51) | <0.01 |
| Arrhythmias | 487 (10) | 421 (10) | 66 (8) | 0.01 |
| Congestive heart failure | 1030 (20) | 903 (21) | 127 (14) | <0.01 |
| Cerebrovascular disease | 290 (6) | 240 (6) | 50 (6) | 0.99 |
| Ischemic heart disease (without myocardial infarction) | 1066 (21) | 946 (22) | 120 (14) | <0.01 |
| Myocardial infarction | 518 (10) | 446 (11) | 72 (8) | 0.02 |
| Chronic obstructive pulmonary disease | 440 (9) | 387 (9) | 53 (6) | <0.01 |
| Drug/alcohol dependence | 127 (2) | 110 (3) | 17 (2) | 0.20 |
| Gastrointestinal bleeding | 30 (1) | 28 (1) | 2 (0) | 0.03 |
| Hepatitis | 225 (4) | 210 (5) | 15 (2) | <0.01 |
| Pneumonia | 104 (2) | 80 (2) | 24 (3) | 0.15 |
| Other infection | 852 (17) | 752 (18) | 100 (11) | <0.01 |
| Hyperparathyroidism | 348 (7) | 273 (6) | 75 (9) | 0.04 |
| Peripheral artery disease/vascular disease | 580 (11) | 491 (12) | 89 (10) | 0.19 |
| Catheter access use | 3068 (60) | 2244 (53) | 836 (95) | <0.01 |
| Presence of any residual renal function | 4551 (89) | 3726 (88) | 783 (89) | 0.71 |
| Mean serum sodium (mmol/L) | 138.8 ± 2.8 | 138.5 ± 2.7 | 139.9 ± 2.9 | <0.01 |
| Mean albumin (g/dL) | 3.7 ± 0.4 | 3.7 ± 0.4 | 3.7 ± 0.4 | 0.33 |
| Mean hemoglobin (g/dL) | 10.7 ± 0.9 | 10.7 ± 0.8 | 11 ± 1.2 | <0.01 |
| Mean systolic blood pressure (mmHg) | 142.4 ± 15.9 | 142.5 ± 15.6 | 141.3 ± 22 | 0.48 |
| Mean body mass index (kg/m2) | 30.4 ± 9.1 | 30.4 ± 9.2 | 30 ± 6.3 | 0.34 |
| Mean physical composite summary score (PCS) | 38.6 ± 10.4 | 38 ± 10.3 | 41.1 ± 10.5 | <0.01 |
| Mean mental composite summary score (MCS) | 51.7 ± 10 | 51.8 ± 10 | 51.4 ± 9.7 | 0.27 |
| Mean symptom problem score (SPS) | 81 ± 14.1 | 80.7 ± 14.3 | 82.7 ± 13.4 | <0.01 |
| Mean burden of kidney disease score (BKD) | 54 ± 28 | 53.2 ± 28 | 58 ± 27.6 | <0.01 |
| Mean effects of kidney disease score (EKD) | 77.2 ± 19.8 | 76.6 ± 20.1 | 79.7 ± 17.7 | <0.01 |
*Categorical variables are presented as numbers (percentages); continuous variables are presented as mean ± standard deviation