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. 2019 Jan 8;19:10. doi: 10.1186/s12935-019-0725-1

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Comparison of genomic profiles between two LGSC cell cultures and their associated LGSC tumor samples. Each graph represents the copy-number (CN) changes detected per chromosome in each sample. Top graphs correspond to LGSC patient #6; CN changes detected in one of her recurrent tumor tissues was compared to the CN changes detected in the primary cell culture derived from this tissue. Bottom graphs correspond to the LGSC patient #9; CN changes detected in one of her recurrent tumor tissues was compared to the CN changes detected in the cell line established from a later recurrent tissue. High genomic profile correlation was observed between cells and tumors in both cases