Fig. 5.

mAb A treatment enhances insulin signalling in the heart post-MI. a Representative blots for insulin signalling kinases. Densiometric analysis for b phosphorylated insulin receptor substaret-1 (p-IRS-1^Tyr628)/IRS-1, c phosphorylated protein kinase B (p-Akt^Ser473)/Akt, d phosphorylated glycogen synthase kinase-beta (p-GSK-3β^Ser9)/GSK-3β, e phosphorylated Akt substrate 160 (AS160^Thr642)/AS160 f glucose transporter type-4 (GLUT4)/α-tubulin, and g phosphorylated pyruvate dehydrogenase (p-PDH-E1α^Ser293)/PDH. Protein bands were normalised for either to their correspondent total protein band or to α-tubulin bands for intra-experiment variation. *p < 0.05. n = 6/group. S sham, V vehicle, Ab mAb A, MI myocardial infarction