Table 2.

Comparison of cpRNFL thickness, GCIPL thickness and asymmetry measurements, and ONH parameters between two groups

Parametres	Normal (n = 67)	PPG (n = 67)	P value
cpRNFL Thickness
Average	96.0 ± 9.2	86.8 ± 8.7	< 0.001
Superior	115.1 ± 16.4	104.2 ± 15.3	< 0.001
Nasal	65.1 ± 10.2	64.4 ± 12.2	0.712
Inferior	119.8 ± 17.1	105.9 ± 16.1	< 0.001
Temporal	83.0 ± 14.6	73.7 ± 12.7	< 0.001
GCIPL Thickness
Average	80.6 ± 5.9	76.2 ± 6.6	< 0.001
Minimum	77.9 ± 6.7	71.8 ± 9.0	< 0.001
Superonasal	82.8 ± 6.7	80.0 ± 9.0	0.043
Superior	81.1 ± 6.6	77.4 ± 7.8	0.004
Superotemporal	80.1 ± 5.4	75.5 ± 7.2	< 0.001
Inferotemporal	80.8 ± 5.6	73.5 ± 7.5	< 0.001
Inferior	77.8 ± 6.6	72.7 ± 7.4	< 0.001
Inferonasal	80.9 ± 7.0	78.0 ± 7.8	0.024
GCIPL Absolute Difference
I–S	6.1 ± 4.2	12.3 ± 13.6	0.001
IT–ST	2.5 ± 1.7	5.2 ± 5.5	< 0.001
T–N	6.9 ± 4.5	11.9 ± 8.9	< 0.001
IT–SN	3.7 ± 2.4	8.2 ± 7.2	< 0.001
IT–IN	3.3 ± 2.8	6.5 ± 5.6	< 0.001
ST–IN	3.7 ± 3.4	5.0 ± 4.4	0.048
GCIPL Asymmetry Ratio
I/S	0.98 ± 0.03	0.97 ± 0.08	0.109
IT/ST	1.01 ± 0.04	0.98 ± 0.10	0.019
T/N	0.98 ± 0.05	0.95 ± 0.08	0.002
IT/SN	0.98 ± 0.05	0.93 ± 0.11	0.001
IT/IN	1.00 ± 0.06	0.95 ± 0.09	< 0.001
ST/IN	0.98 ± 0.07	0.97 ± 0.09	0.118
GCIPL Asymmetry Index
Log10 (I/S)	0.01 ± 0.01	0.02 ± 0.03	0.001
Log10 (IT/ST)	0.01 ± 0.01	0.03 ± 0.03	< 0.001
Log10 (T/N)	0.02 ± 0.01	0.03 ± 0.03	< 0.001
Log10 (IT/SN)	0.02 ± 0.01	0.05 ± 0.04	< 0.001
Log10 (IT/IN)	0.00 ± 0.02	0.04 ± 0.03	< 0.001
Log10 (ST/IN)	0.02 ± 0.02	0.03 ± 0.03	0.026
ONH
Rim Area	1.21 ± 0.23	1.05 ± 0.19	< 0.001
Disc Area	1.78 ± 0.50	1.98 ± 0.50	< 0.001
Average C/D	0.50 ± 0.20	0.63 ± 0.18	< 0.001
Vertical C/D	0.47 ± 0.20	0.60 ± 0.18	< 0.001
Cup Volume	0.18 ± 0.15	0.36 ± 0.26	< 0.001

PPG, preperimetric glaucoma; GCIPL, ganglion cell-inner plexiform layer; cpRNFL, circumferential peripapillary retinal nerve fiber layer; ONH, optic nerve head; C/D, cup-to-disc ratio; I, inferior hemisphere; S, superior hemisphere; IT, inferotemporal; ST, superotemporal; T, temporal; N, nasal; SN, superonasal; IN, inferonasal