Figure 2.

Features of iProteinDB user interface. Observed PTM sites are marked in red on the Drosophila melanogaster protein sequence. Predicted phosphosites based on phospho-proteomic data from five other Drosophila species are marked in blue. Sites observed in more than one Drosophila species are underlined. The protein domains are highlighted in green. The data sources of PTMs are summarized. At the “Predicted Orthologs” page, the multiple sequence alignment of orthologous genes of major model organisms and human are displayed with observed sites color-coded (red arrows), conserved sites bolded (brown arrow) and human disease variant mutations underlined (navy arrows).