Table 1. Major spermatogenesis-specific FBF targets, from Block I.
RNA | Biochemical functiona | Biological functionb | References | |
---|---|---|---|---|
1 | fog-3 | Tob/BTG RNA regulator | Sperm fate specification | Ellis and Kimble (1995) |
2 | F58F12.2 | Predicted transmembrane protein | Unknown | Krogh et al. (2001); Petersen et al. (2011) |
3 | gska-3 | MOK protein kinase | Development | Mulder et al. (2003) |
4 | W02B12.12 | Testis-specific serine/threonine-protein kinase | Unknown | WormBase |
5 | C56G2.5 | Kinase | Unknown | WormBase |
6 | ZK622.1 | Ortholog of human FER tyrosine kinase | Unknown | WormBase |
7 | C35E7.10 | FER tyrosine kinase (non-receptor) | Viability | WormBase |
8 | moa-1 | Tyrosine phosphatase | Unknown | Ewald et al. (2012) |
9 | osta-1 | Solute carrier family 51, alpha subunit | Cilia morphology | Olivier-Mason et al. (2013) |
10 | glo-4 | Guanine nucleotide exchange factor | Viability | Hermann et al. (2005) |
11 | Y57G11A.2 | Vitelline membrane outer layer protein | Unknown | WormBase |
12 | snpc-1.3 | Ortholog of human SNAPC1 | Unknown | WormBase |
13 | ZK973.8 | BTB/POZ domain protein | Neural development | WormBase |
14 | F27C8.5 | BTB/POZ domain protein | Unknown | Mulder et al. (2003) |
15 | linc-36 | lincRNA | Unknown | WormBase |
16 | glct-6 | Glucuronyltransferase | Life span | Kim and Sun (2007) |
17 | pitr-5 | Phosphate transporter | Unknown | WormBase |
18 | ZK686.5 | C2H2-like zinc finger | Unknown | WormBase |
19 | C42C1.3 | Novelc | Fertility | Sun et al. (2011) |
20 | D1081.12 | Novelc | Unknown | WormBase |
21 | C06C3.10 | Novelc | Unknown | WormBase |
22 | ttr-9 | Transthyretin-like proteinc | Unknown | WormBase |
23 | ZK637.12 | Novel | Unknown | WormBase |
24 | C35A11.2 | Novel, with signal peptide | Unknown | WormBase |
25 | C44B9.2 | Novel | Unknown | WormBase |
26 | C09H10.9 | Novel | Unknown | WormBase |
27 | F42G4.2 | Novel | Unknown | WormBase |
28 | F52F12.5 | Novel | Unknown | WormBase |
29 | T05F1.5 | Novel | Unknown | WormBase |
Biochemical functions are predicted from protein domains or homology with characterized proteins.
Biological functions are deduced from mutant phenotypes.
Protein contains an N-terminal transmembrane helix.