Fig. 2.

Pharmacokinetic profiles for somapacitan, with final model fit a for a single dose in healthy adults; b at steady state in healthy adults; c a single dose in subjects with AGHD; d at steady state in subjects with AGHD; and e for a single dose in children with GHD. Somapacitan concentration versus time profiles. Panels a, c, and e show single-dose and panels b and d show steady-state profiles for each dose group in trials of healthy adults (NCT01514500), subjects with AGHD (NCT01706783), and children with GHD (NCT01973244). Points are geometric mean with 95% confidence intervals. Lines are population predictions. AGHD adult growth hormone deficiency, GHD growth hormone deficiency