Table 1.
Operationalization of the original Asthma Predictive Index (API)
| Original Asthma Predictive Index | Operationalized Asthma Predictive Index |
|
|---|---|---|
| Early frequent wheezer | Parental report - a value ≥3 in the scale (scale: 1 to 5, from “very rarely” to “on most days”) |
≥2 wheezing episodes at any given time on history or examination with at least 3 weeks of interval |
| Parental asthma a | Parental report (diagnosed by a physician) | Parental history of asthma documented |
| Eczema | Parental report (diagnosed by a physician) | Physician-diagnosed atopic dermatitis or eczema documented |
| Allergic rhinitis | Parental report (diagnosed by a physician) - Hay fever or any other condition that made a child’s nose stuffy, itchy, or runny apart from colds during the first 3 years of life and whether a doctor had said that these symptoms were due to allergies. |
Physician-diagnosed allergic rhinitis or hay fever documented |
| Wheezing apart from cold | Parental report | Wheezing documented without any symptom of cold b |
| Eosinophilia (≥4%) | Blood specimens obtained around at 1 year of age (10.9±0.6 month) | Blood specimen obtained up to the last follow-up date |
| Asthma Index date | N/A | The date when operationalized API was all met. |
a
Parental history of asthma was reviewed up to the last follow-up date.
b
“Cold” was defined by upper respiratory infection or Cold documented, OR fever (≥100.4◦F) plus runny/stuffy nose.