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. 2018 Sep 25;3:192–248. doi: 10.1016/j.idm.2018.08.001

Table 5.

A summary of our results for application of PGFs to the final size and large-time dynamics of SIR disease. The PGFs χ and ψ encode the heterogeneity in susceptibility. The PGF χ is the PGF of the ancestor distribution (an ancestor of u is any individual who, if infected, would infect u). The PGF ψ(x)=κp(κ)xκ encodes the distribution of the contact rates.

Question Section Solution
Final size relation for an SIR epidemic assuming a vanishingly small fraction ρ randomly infected initially with ρN1. 4.2 r()=1χ(1r()). [For standard assumptions, including the usual continuous-time assumptions, χ(x)=e0(1x).]

Discrete-time number susceptible, infected, or recovered in a population with homogeneous susceptibility and given 0, assuming an initial fraction ρ is randomly infected with ρN1. 4.3 For g>0:Sg=N1ρeR01Sg1/NIg=NSgRgRg=Rg1+Ig1 with the initial condition S(0)=(1ρ)N, I(0)=ρN, and R(0)=0.

Discrete-time number susceptible, infected, or recovered in a population with heterogeneous susceptibility for SIR disease after g generations with an initial fraction ρ randomly infected where ρN1. 4.3 For g>0:Sg=N1ρχSg1/NIg=NSgRgRg=Rg1+Ig1 with the initial condition S(0)=(1ρ)N, I(0)=ρN, and R(0)=0.

Continuous time number susceptible, infected, or recovered for SIR disease as a function of time with an initial fraction ρ randomly infected where ρN1. Assumes u receives infection at rate βIκu/NK 4.4 For t>0:St=1-ρNψθtIt=N-St-RtRt=γNKβlnθtθ˙t=-βNKIθt with the initial condition θ(0)=1.