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. 2019 Jan 9;14(1):e0209824. doi: 10.1371/journal.pone.0209824

Fig 2. ER stress and terminal UPR signaling precede fibrosis in bleomycin-exposed mice.

Fig 2

(A) Quantitative PCR of UPR markers XBP1, BiP, ATF4, and CHOP from mice at 0, 2, 8, 14, 20, or 26 days after a single exposure to bleomycin. Each mouse is represented by a dot, and whiskers denote group mean +/- SEM. (B) Quantitative PCR for collagen 1A1 mRNA and fibronectin mRNA from at 0, 2, 8, 14, 20, or 26 days after a single exposure to bleomycin. Each mouse is represented by a dot, and whiskers denote group mean +/- SEM. P values: *<0.05, **<0.01, ***<0.001.