Table 2.
Partial nephrectomy (PN) vs radical nephrectomy (RN) (2009–2015)
| Patient data | Univariate | Multivariate | |||
|---|---|---|---|---|---|
| PN (n = 1277), no. (%) | RN (n = 1385), no. (%) | p valuea | RR (95% CI) | p valueb | |
| Median age, years | 60 | 63 | < 0.001 | 0.99 (0.99-0.99) | < 0.001 |
| Hypertension | 808 (63.3) | 951 (68.7) | 0.003 | 1.06 (0.97–1.15) | 0.221 |
| Diabetes | 356 (27.9) | 434 (31.3) | 0.051 | 0.98 (0.89–1.08) | 0.665 |
| Chronic kidney disease (CKD) stage | |||||
| Preoperative CKD 1/2 | 971 (82.4) | 1012 (77.5) | 0.003 | 0.96 (0.85–1.08) | 0.528 |
| Preoperative CKD 3+ | 208 (17.6) | 293 (22.5) | |||
| Cancer stage | |||||
| T1 | 1153 (91.6) | 720 (54.0) | < 0.001 | — | — |
| T2 | 26 (2.1) | 269 (20.2) | 0.14 (0.10–0.20) | < 0.001 | |
| T3 | 80 (6.3) | 344 (25.8) | 0.31 (0.25–0.38) | < 0.001 | |
| Race/ethnicityc | |||||
| White | 630 (49.8) | 697 (50.6) | 0.369 | — | 0.066 |
| Hispanic | 405 (32.0) | 413 (30.0) | 0.96 (0.88–1.04) | ||
| Black | 139 (11.0) | 176 (12.8) | 0.84 (0.74–0.96) | ||
| Asian | 91 (7.2) | 90 (6.5) | 0.98 (0.85–1.14) | ||
| Sex | |||||
| Men | 778 (60.9) | 886 (64.0) | 0.105 | — | — |
| Women | 499 (39.1) | 499 (36.0) | 1.03 (0.96–1.11) | 0.421 | |
| Charlson Comorbidity Index (CCI) | |||||
| CCI 0 | 229 (17.9) | 132 (9.5) | < 0.001 | — | 0.004 |
| CCI 1 | 0.96 (0.82–1.13) | ||||
| CCI 2 | 760 (59.5) | 780 (56.3) | 0.85 (0.75–0.96) | ||
| CCI 3 | 0.89 (0.77–1.01) | ||||
| CCI 4 | 0.87 (0.74–1.02) | ||||
| CCI ≥ 5 | 288 (22.6) | 473 (34.2) | 0.75 (0.64–0.88) | ||
| Year of surgery | |||||
| 2009 | 130 (10.2) | 238 (17.2) | < 0.001 | Adjusted for year of surgery; results not shown | |
| 2010 | 165 (12.9) | 234 (16.9) | |||
| 2011 | 186 (14.6) | 236 (17.0) | |||
| 2012 | 229 (17.9) | 209 (15.1) | |||
| 2013 | 241 (18.9) | 188 (13.6) | |||
| 2014 | 226 (17.7) | 191 (13.8) | |||
a
χ2 tests for independence were used for categorical variables; Wilcoxon rank sum test were used for continuous variables. Boldface values are statistically significant.
b
Based on likelihood ratio statistic. Boldface values are statistically significant.
c
Numbers for race/ethnicity do not sum to 100 because there were insufficient numbers to include those.
CI = confidence interval; RR = relative risk.