Table 3. Stratified analyses between IL-1B gene polymorphisms and risk of colorectal cancer.

Variable	case/control			Homozygous model	Dominant model	Recessive model
Rs1143623	GG	GC	CC	CC vs. GG	CC+GC vs. GG	CC vs. GC+GG
Age (years)
<50	101/94	65/74	8/18	0.44(0.21,0.91); 0.024	0.90(0.64,1.26); 0.530	0.44(0.21,0.90); 0.024
≥50	205/235	123/177	24/39	0.75(0.41,1.37); 0.351	0.67(0.48,0.92); 0.014	0.89(0.50,1.61); 0.709
Sex
Female	122/152	84/90	9/25	0.45(0.20,1.00); 0.049	1.01(0.70,145); 0.967	0.42(0.19,0.93); 0.032
Male	184/177	104/161	23/32	0.69(0.39,1.23); 0.208	0.63(0.47,0.86); 0.003	0.84(0.48,1.47); 0.550
Smoking
No	146/169	81/118	14/21	0.77(0.38,1.57); 0.475	0.79(0.56,1.11); 0.180	0.84(0.42,1.69); 0.631
Yes	160/160	107/133	18/36	0.50(0.27,0.92); 0.025	0.74(0.54,1.02); 0.064	0.55(0.30,0.99); 0.046
Drinking
No	122/156	83/123	14/13	1.38(0.62,3.04); 0.428	0.91(0.64,1.30); 0.608	1.47(0.67,3.19); 0.334
Yes	184/173	105/128	18/44	0.39(0.21,0.69); 0.001	0.67(0.49,0.92); 0.012	0.43(0.24,0.76); 0.004
Rs1143634	CC	CT	TT	TT vs. CC	TT+CT vs. CC	TT vs. CT+CC
Age (years)
<50	128/133	45/47	1/6	0.34(0.09,1.25); 0.104	0.88(0.60,1.27); 0.484	0.34(0.09,1.26); 0.108
≥50	271/314	74/121	7/16	0.46(0.16,1.34); 0.155	0.64(0.44,0.93); 0.018	0.51(0.18,1.47); 0.212
Sex
Female	155/185	55/66	4/15	0.32(0.10,0.98); 0.046	0.87(0.58,1.29); 0.490	0.32(0.10,0.98); 0.045
Male	244/262	64/102	4/7	0.61(0.18,2.12); 0.440	0.67(0.47,0.95); 0.025	0.68(0.20,2.33); 0.534
Smoking
No	181/225	56/74	4/9	0.55(0.17,1.82); 0.330	0.90(0.61,1.32); 0.587	0.56(0.17,1.84); 0.341
Yes	218/222	63/94	4/13	0.31(0.10,0.98); 0.045	0.64(0.45,0.91); 0.014	0.35(0.11,1.07); 0.066
Drinking
No	170/206	45/79	3/7	0.52(0.13,2.04); 0.348	0.68(0.45,1.02); 0.060	0.57(0.15,2.22); 0.417
Yes	229/241	74/89	5/15	0.35(0.13,0.98); 0.046	0.80(0.57,1.13); 0.202	0.36(0.13,1.01); 0.053

Bold values are statistically significant (P < 0.05)