Table 3. Enrichment analysis of the effect of FoxM1 expression on related signaling pathways in ICC.
No. | Signaling pathways | ES | NES | Nom P-value | FDR q-value |
1 | PID_MYC_PATHWAY | 0.583 | 1.705 | 0.016 | 0.089 |
2 | PID_MYC_ACTIV_PATHWAY | 0.601 | 1.973 | 0.000 | 0.009 |
3 | PID_ATM_PATHWAY | 0.635 | 1.871 | 0.001 | 0.026 |
4 | PID_ATR_PATHWAY | 0.745 | 2.121 | 0.000 | 0.001 |
5 | PID_MET_PATHWAY | 0.463 | 1.464 | 0.098 | 0.225 |
6 | KEGG_P53_SIGNALING_PATHWAY | 0.612 | 2.079 | 0.000 | 0.003 |
7 | PID_P53_REGULATION_PATHWAY | 0.545 | 1.728 | 0.004 | 0.077 |
8 | PID_P53_DOWNSTREAM_PATHWAY | 0.472 | 1.744 | 0.003 | 0.071 |
9 | PID_WNT_CANONICAL_PATHWAY | 0.574 | 1.547 | 0.050 | 0.172 |
10 | REACTOME_SIGNALING_BY_WNT | 0.528 | 1.555 | 0.081 | 0.169 |
11 | REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS | 0.537 | 1.643 | 0.020 | 0.129 |
12 | PID_TELOMERASE_PATHWAY | 0.476 | 1.539 | 0.051 | 0.170 |
13 | PID_TAP63_PATHWAY | 0.471 | 1.568 | 0.031 | 0.165 |
14 | PID_PLK1_PATHWAY | 0.791 | 2.076 | 0.000 | 0.003 |
15 | PID_P38_MK2_PATHWAY | 0.550 | 1.524 | 0.040 | 0.178 |
16 | PID_FOXO_PATHWAY | 0.532 | 1.561 | 0.047 | 0.167 |
17 | PID_BARD1_PATHWAY | 0.759 | 1.983 | 0.000 | 0.009 |
Abbreviations: ES, enrichment Score; NES, normalized enrichment score; Nom P-value, nominal p-value; FDR q-value, false discovery rate q-value. FDR q-value < 0.250 was considered different.