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. 2018 Dec 18;10(12):4269–4288. doi: 10.18632/aging.101721

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Copyright © 2018 Anisimova et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY) 3.0 License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Molecular pathways modulating lifespan via control of the translation machinery. Components of the Ras/MEK/ERK signaling pathway are shown in yellow, those of the PI3K/Akt/mTOR axis in green, the ISR pathway in yellow, and the translation machinery components in grey [80,166,175,180].