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. 2018 Oct 1;47(1):e5. doi: 10.1093/nar/gky874

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© The Author(s) 2018. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Nucleotide sequence context of rNMPs embedded in the nuclear and mitochondrial DNA of a RNase H2-defective strain of Saccharomyces cerevisiae obtained using the Sequence Module of Ribose-Map. Embedded rNMPs were tagged and sequenced using ribose-seq. The nucleotide frequencies are normalized to those of the reference genome. The nucleotide frequencies are shown relative to the sites of embedded rNMPs (position 0 = rNMP site). (A and B) Zoomed-out (100 bases up/downstream from rNMP sites) for all rNMPs combined, (C and D) zoomed-in (15 bases up/downstream from rNMP sites) for all rNMPs combined, (E) zoomed-in for rGMP and (F) zoomed-in for rUMP.