Table 4.
Utility of different blood pressure measurement components and their combinations in childhood to predict adult high cIMT (age-, sex- and study-specific ≥ 90th percentile).
| Method for prediction |
Diastolic V | Diastolic IV | P for difference |
|---|---|---|---|
| AUC (95%CI) | 0.669 (0.646–0.693) | 0.670 (0.647–0.694) | 0.37 |
| IDI | 0.0012 | 0.002 | |
| NRI | 0.05 | 0.25 | |
| Systolic | Systolic + Diastolic V | P for difference | |
| AUC (95%CI) | 0.677 (0.657–0.704) | 0.678 (0.655–0.700) | 0.32 |
| IDI | 0.0001 | 0.78 | |
| NRI | 0.007 | 0.12 | |
| Systolic | Systolic + PP V* | P for difference | |
| AUC (95%CI) | 0.677 (0.657–0.704) | 0.678 (0.655–0.700) | 0.40 |
| IDI | 0.0001 | 0.70 | |
| NRI | 0.072 | 0.10 | |
| PP V* | PP V* + MAP V* | P for difference | |
| AUC (95%CI) | 0.673 (0.651–0.694) | 0.677 (0.655–0.699) | 0.09 |
| IDI | 0.002 | 0.005 | |
| NRI | 0.066 | 0.15 | |
| MAP V* | PP V* + MAP V* | P for difference | |
| AUC (95%CI) | 0.667 (0.645–0.689) | 0.677 (0.655–0.699) | 0.005 |
| IDI | 0.035 | 0.001 | |
| NRI | 0.15 | 0.011 | |
| PP V* + MAP V* | Systolic + Diastolic V | P for difference | |
| AUC (95%CI) | 0.677 (0.655–0.699) | 0.678 (0.656–0.700) | 0.25 |
| IDI | 0.0003 | 0.23 | |
| NRI | 0.014 | 0.76 | |
*
Diastolic V was used in the MAP V and PP V models
AUC: Area under the curve, IDI: integrated discrimination index, NRI: net reclassification index; MAP: mean arterial pressure, PP: pulse pressure, cIMT: carotid intima-media thickness