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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: FEBS J. 2018 Dec 22;286(1):82–109. doi: 10.1111/febs.14728

Figure 11: H3K4me3 peak presence near a known gene in neonatal monocytes was a good predictor of active gene transcription.

Figure 11:

A) Total consensus H3K4me3 peaks that annotate to known genes in healthy and chorioamnionitis-exposed term neonatal monocytes compared to known annotated mRNA transcripts. mRNA expression was defined as a normalized read count of >10. Consensus H3K4me3 peaks that annotated to known genes compared to quantitative normalized mRNA transcript levels at B) promoter sites, C) introns and D) intergenic sites. U(n=3)=term healthy unstimulated monocytes, CU(n=2)=term chorioamnionitis-exposed unstimulated monocytes, L(n=3)=term healthy LPS stimulated monocytes, CL(n=3)=term chorioamnionitis-exposed LPS stimulated monocytes. Chi-square test was used to evaluate differences in proportions between groups, ****p<0.0001.