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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: FEBS J. 2018 Dec 22;286(1):82–109. doi: 10.1111/febs.14728

Table 8:

Gene ontology pathways enriched for differentially expressed transcripts

Groups Increased in Group GO Term Term Ontology DEe Genes in Pathway p-value Benjamini
Ua vs Lb
U 0003676 Nucleic acid binding MF 29 8.3E-6 2.8E-3
U 0046872 Metal ion binding MF 45 3.4E-5 5.6E-3
L 0005615 Extracellular space CC 32 1.3E-5 2.6E-03
L 0005125 Cytokine activity MF 10 6.5E-5 2.0E-02
L 0006954 Inflammatory response BP 15 3.7E-5 4E-2
CUc vs CLd
U None None None None None None
L None None None None None None
Ua vs CUc
U None None None None None None
CU 0015671 Oxygen transport BP 6 7.1E-9 3.3E-6
CU 0005344 Oxygen transporter activity MF 6 3.8E-9 6E-7
CU 0015701 Bicarbonate transport BP 7 6.9E-8 1.6E-05
Lb vs CLd
L None None None None None None
CL 0005344 Oxygen transporter activity MF 8 3.9E-10 1.4E-07
CL 0015671 Oxygen transport BP 8 7.5E-10 8.6E-07
CL 0019825 Oxygen binding MF 9 3.4E-7 6.2E-05
CL 0005506 Iron ion binding MF 11 8.1E-5 9.7E-03
a

U=term healthy unstimulated monocytes,

b

L=term healthy LPS stimulated monocytes,

c

U=term chorioamnionitis-exposed unstimulated monocytes,

d

CL=term chorioamnionitis-exposed LPS stimulated monocytes,

e

DE=differentially expressed