Figure 1.

DNA methylation (DNAm) age residuals for youth as a function of the number of types of A) threat experiences and B) deprivation experiences. Scatterplots with regression lines and 95% confidence intervals, along with R-squared (R²) values, are shown. Figures 1A and 1B present unadjusted associations. Figures 1C and 1D present associations with threat and deprivation experiences residualized on covariates in the fully adjusted model (sex, race/ethnicity, family poverty status, and other dimension of early life adversity), respectively. Positive DNAm age residuals indicate accelerated DNAm age relative to chronological age.