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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Biol Psychiatry. 2018 Sep 26;85(3):268–278. doi: 10.1016/j.biopsych.2018.09.008

Table 4.

Regression parameters and 95% confidence intervals for associations of early life adversity experiences of threat and deprivation and biological aging metrics with depressive symptoms and externalizing problems.

Depressive Symptoms Externalizing Problems
b (95% CI) β p n b (95% CI) β p n
Threat  1.04 (0.80–1.28)  0.51 <.0001 225  1.54 (1.18–1.90)  0.53 <.0001 225
exposure scorea
Deprivation  2.75 (1.82–3.67)  0.39 <.0001 227  4.78 (3.47–6.09)  0.48 <.0001 227
exposure scorea
DNAm age
 Model 1a  0.42 (0.14–0.70)  0.26 .004 190  0.36 (−0.05–0.78)  0.16 .084 190
 Model 2b  0.26 (0.01–0.52)  0.16 .040 186  0.15 (−0.22–0.52)  0.06 .434 186
Tanner stage
 Model 1a  0.34 (−0.92–1.61)  0.06 .594 208  0.49 (−1.27–2.25)  0.06 .584 208
 Model 2b −0.53 (−1.67–0.61) −0.09 .359 204 −0.53 (−2.02–0.97) −0.07 .490 204

Note. CI=confidence interval. DNAm=DNA methylation.

a

Model adjusted for age, sex, race/ethnicity, and family poverty status.

b

Model 1 further adjusted for threat exposure.