Table 2.

Characteristics of female NPYKO mice (Mean ± SEM)

Measurement	WT n=7	NPYKO n=6
Metabolic
Body weight (g)	20.87±0.18	26.22±1.78**
Lean mass (g)	15.23±0.11	16.78±0.61*
Fat mass (g)	3.30±0.18	7.18±1.26**
% Fat mass	17.7±0.9	29.2±3.0*
Leptin levels (ng/mL)	2.26±0.4	6.63±1.7*
Bone
Femur length	14.97±0.08	14.75±0.12
Total area (mm2)	1.67±0.02	1.66±0.05
Marrow area (mm2)	0.98±0.01	0.97±0.04
Cortical area (mm2)	0.69±0.01	0.69±0.02
Cortical thickness (mm)	0.158±0.003	0.161±0.002
Periosteal perimeter (mm)	4.67±0.04	4.65±0.07
Endosteal perimeter (mm)	3.50±0.03	3.48±0.06
BV/TV (%)	4.8±0.8	5.0±0.8
Trabecular thickness (μm)	49.0±1.1	48.3±1.6
Trabecular number (1/mm)	3.3±0.1	3.4±0.1

^*Student’s t-test

^*p<0.05

^**p<0.01 when compared to WT.