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. Author manuscript; available in PMC: 2020 Jan 15.
Published in final edited form as: Acta Biomater. 2018 Dec 1;84:169–179. doi: 10.1016/j.actbio.2018.11.030

Fig. 1.

Fig. 1.

Storage modulus of HA hydrogels is not affected by peptide functionalization. (A) G’ significantly increased as HA concentration increased from 1 – 3 % (w/v). Oscillatory shear stress was performed at 1 rad/sec and G’ determined at an oscillatory shear stress of 10 Pa. Two-way ANOVA indicated that %HA significantly affected G’ (p < 0.05), whereas functionalization with 294 μM peptide did not. Tukey’s post-hoc test revealed significant differences between G’ of different gel percentages (*p < 0.05, **p < 0.01, ***p < 0.001). (B) Loss modulus, G”, was significantly lower than G’ indicating that hydrogel mechanics is dominated by the elastic behavior. Two-way ANOVA indicated significant difference between G’ and G’’ (p < 0.0001). Tukey’s post-hoc test revealed significant differences between G’ and G’’ of the same %HA hydrogel (***p < 0.0001). (C) Functionalization of 1% HA with 0 – 588 μM peptide did not significantly affect G’. Error bars = SD, n = 4 for each treatment.