Table 3.

In-degree, out-degree statistical comparisons among groups

Vertex	In-degree			Out-degree
	Main effect	p value from post-hoc		Main effect	p value from post-hoc
	H(2,125)	Controls versus AD-MCI	Controls versus ADD	H(2,125)	Controls versus AD-MCI	Controls versus ADD
Fp1	H = 2.87, p = 0.2	n.a.	n.a.	H = 6.23, p = 0.04	n.s.	n.s.
Fp2	H = 5.70, p = 0.06	n.a.	n.a.	H = 6.52, p = 0.04	n.s.	n.s.
F7	H = 4.70, p = 0.1	n.a.	n.a.	H = 10.02, p = 0.007	0.02	0.02
F3	H = 3.06, p = 0.2	n.a.	n.a.	H = 5.38, p = 0.07	n.a.	n.a.
Fz	H = 6.36, p = 0.04	n.s.	n.s.	H = 5.67, p = 0.06	n.a.	n.a.
F4	H = 6.96, p = 0.03	n.s.	0.03	H = 6.61, p = 0.04	n.s.	n.s.
F8	H = 9.87, p = 0.007	0.01	0.03	H = 9.99, p = 0.007	0.007	n.s.
T3	H = 6.85, p = 0.03	0.03	n.s.	H = 12.53, p = 0.002	0.001	n.s.
C3	H = 7.38, p = 0.03	0.047	n.s.	H = 1.42, p = 0.5	n.a.	n.a.
Cz	H = 9.19, p = 0.01	0.01	n.s.	H = 10.66, p = 0.005	0.01	0.02
C4	H = 13.11, p = 0.001	0.002	0.022	H = 2.26, p = 0.3	n.a.	n.a.
T4	H = 10.74, p = 0.005	0.003	n.s.	H = 7.25, p = 0.03	n.s.	n.s.
T5	H = 11.88, p = 0.003	0.005	0.02	H = 6.22, p = 0.045	n.s.	n.s.
P3	H = 14.41, p = 0.001	0.003	0.003	H = 7.30, p = 0.03	0.04	n.s.
Pz	H = 11.65, p = 0.003	0.04	0.003	H = 3.95, p = 0. 1	n.a.	n.a.
P4	H = 12.40, p = 0.002	0.007	0.007	H = 7.63, p = 0.02	0.04	n.s.
T6	H = 11.28, p = 0.004	0.006	0.02	H = 11.78, p = 0.003	0.006	0.02
O1	H = 8.02, p = 0.02	0.04	0.046	H = 8.85, p = 0.01	0.02	0.05
O2	H = 7.44, p = 0.02	n.s.	n.s.	H = 4.09, p = 0.1	n.a.	n.a.

For each vertex, main effect results and adjusted p values for multiple comparisons are shown for post-hoc analysis

ADD Alzheimer’s disease with dementia, AD-MCI mild cognitive impairment due to Alzheimer’s disease, n.a. not applicable following not significant main effect, n.s. not significant