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. 2018 Jun;17(5):389–399. doi: 10.2174/1871527317666180525113109

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© 2018 Bentham Science Publishers

This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

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Fig. (3) — Expression of CaMKII, PKC, NMDAR2B, BDNF, TrkB, and CREB protein (cropped blots from different gels). (A) Compared with that in the sham operation group, the expression of CaMKII was significantly lower in the model group (P=0.0001). While compared with that in the model group, the expression of CaMKII was significantly higher in the OA group (P=0.0001), and higher than that in sham group (P=0.0001); (B) compared with that in the sham operation group, the expression of PKC was significantly lower in the model group (P=0.026). While compared with that in the model group, the expression of PKC was significantly higher in the OA group (P=0.036); (C) compared with that in the sham operation group, the expression of NMDAR2B was significantly lower in the model group (P=0.001). While compared with that in the model group, the expression of NMDAR2B was significantly higher in the OA group (P=0.041), but still significantly lower than that in sham group (P=0.018); (D) compared with that in the sham operation group, the expression of BDNF was significantly lower in the model group (P=0.0001). While compared with that in the model group, the expression of BDNF was significantly higher in the OA group (P=0.0001); (E) compared with that in the sham operation group, the expression of TrkB was significantly lower in the model group (P=0.0001). While compared with that in the model group, the expression of TrkB was significantly higher in the OA group (P=0.0001), but still significantly lower than that in sham group (P=0.0001); (F) compared with that in the sham operation group, the expression of CREB was significantly lower in the model group, with statistically significant difference (P=0.0001). While compared with that in the model group, the expression of CREB was significantly higher in the OA group, with statistically significant difference (P=0.0001), but still significantly lower than that in sham group (P=0.0001).

Notes: *indicates compared with that in the sham operation group, P<0.05;

#indicates compared with that in the model group, P<0.05.