Table IV:
Interference by added t-PA and grades for dose response curves
| Assay Number | mean decrease | Grade for dose-response |
|---|---|---|
| due to t-PA addition | ||
| relative to pre-value | ||
| Category I | ||
| 3 | 44% | A |
| 12 | 60% | C |
| 14 | 13% | B |
| Category II | ||
| 1 | 34% | A |
| 2 | 83% | A |
| 10 | 0% | B |
| 13 | 34% | A |
| 15 | 42% | A |
| Category III | ||
| 16 | –11 % | B |
| 5 | 35 % | A |
| 6 | 39 % | C |
| 7 | 42 % | B |
| 8 | -13 % | C |
| 9 | - | B |
| 11 | 93 % | C |
| 16 | 9 % | B |
| 17 | 11 % | A |
The decrease in PAI-1 activity by added t-PA is recorded as a percentage of the initial value. Average, theoretical maximal decrease relative to the pre-value is~ 50%. The value shown is the mean of the data of added t-PA to sample H and J. Bold values fulfil the criterium grade A.